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A Case of Acute Necrotizing Fasciitis Following Internal Jugular Vein Thrombophlebitis: Lemierre¡¯s Syndrome

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±èÇöÁ¤, Besana Aaron, ÀÓÈ£°æ, ÀåÇö¼®, ¹Úµ¿¼®, ÀÌÀǼ®,
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±èÇöÁ¤ ( Kim Hyun-Jung ) - Korea University Department of Oral and Maxillofacial Surgery
 ( Besana Aaron ) - Korea University Department of Oral and Maxillofacial Surgery
ÀÓÈ£°æ ( Lim Ho-Kyung ) - Korea University Department of Oral and Maxillofacial Surgery
ÀåÇö¼® ( Jang Hyon-Seok ) - Korea University Department of Oral and Maxillofacial Surgery
¹Úµ¿¼® ( Park Dong-Suk ) - National Academy of Agricultural Science Department of Agricultural Biotechnology
ÀÌÀǼ® ( Lee Eui-Seok ) - Korea University Department of Oral and Maxillofacial Surgery

Abstract


Lemierre¡¯s syndrome is caused by preexisting oropharyngeal infection and characterized by internal jugular vein (IJV) thrombophlebitis. Frequently, this syndrome involves metastatic infection in areas such as the peritoneum, muscles, and spleen. The most common etiologic organism is Fusobacterium necrophorum. In this case, a masticatory space abscess that originated from a tooth caused the IJV thrombophlebitis. The patient had preexisting hypertension, diabetes mellitus, hyperlipidemia, and Parkinson¡¯s disease. Blood culture revealed Streptococcus sanguinis, and the patient received antibiotics that were highly sensitive to mentioned bacterium; additionally, an anticoagulant was used. With the widespread use of antibiotics, Lemierre¡¯s syndrome has become uncommon, and related mortality rates have noticeably decreased. This has led the public to forget about the disease, but it can still be potentially fatal without early diagnosis and ppropriate antibiotic treatment.

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Lemierre¡¯s syndrome; Internal jugular vein; Thrombophlebitis

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